Biospace Lab at the Pasteur institute metabolomics workshop, June 27th 2019

Biospace Lab were proud to present their autoradiographic solutions for the analysis of proteins lipids and sugars at Pasteur Institute’s Metabolomics Workshop on Thursday June 27th 2019.

You may watch the presentation on Biospace Lab’s New Youtube channel at :

PhotonIMAGER OPTIMA installation - University of Warwick, UK

Biospace lab are pleased to announce the installation of a brand new PhotonIMAGER OPTIMA System at the University of Warwick, UK. 

Warwick University

The system’s real-time capabilities will be used to monitor fluctuations of bioluminescent and fluorescent genetic reporters to study the pathophysiological roles of biological clocks in the Dallmann Lab, the biodistribution and AMR properties of nanoparticles in the Perrier Lab and the role of immune cells in endometriosis in the Grieves Lab.

P-Lumin module installation - Universite Paris Descartes

Biospace lab are proud to announce the 1st installation of the P-Lumin module for the Photon-IMAGERTM OPTIMA at UTCBS in the Life Imaging Platform (LIV), Small animal Optical Imaging Laboratory (LIOPA), Faculty of Pharmacy, Université Paris Descartes, France.

The P-Lumin module is designed for reproductible in vivo imaging of persistent luminescence nanoparticles in longitudinal studies1,2,3.

The module is equipped with high intensity LED backlights to excite the nanoparticles within the animal tissues. The backlights are placed close to the animal for optimal illumination rate. Simultaneous acquisition of luminescence signals from two mice allows for comparative analysis. Thermoregulation of the animals is ensured via a heated bed.

A dedicated P-Lumin interface within the PhotoAcquisitionTM software allows control of various acquisition parameters (excitation duration & intensity, acquisition time, etc.) in a precise and reproducible manner.

Real-time capabilities of the PhotonIMAGERTM Optima allow monitoring of nanoparticle biodistribution and light emission decay throughout the acquisition.

The M3VisionTM analysis software is dedicated to accurate quantification of the temporal data (time profile analysis, temporal window quantification, sequence movie export, etc).

The development of the P-Lumin module was a collaborative project between Biospace lab and the Chemical and Biological Technologies for Health Unit (UTCBS), CNRSUMR 8258 INSERMU1022 and was financed by the French national research agency ANR-PEPSI (ANR14-CE08-0016).

  1. Teston et al, Nanohybrids with Magnetic and Persistent Luminescence Properties for Cell Labeling, Tracking, In Vivo Real-Time Imaging, and Magnetic Vectorization,Small, 2018. DOI:10.1002/smll.201800020.
  2. Lécuyeret al, Chemically engineered persistent luminescence nanoprobes for bioimaging,Theranostics, 2016,DOI: 10.7150/thno.16589.
  3. Maldineyet al, The in vivo activation of persistent nanophosphors for optical imaging of vascularization, tumours and grafted cells, Nature materials, 2014 DOI: 10.1038/NMAT3908.

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