PUBLICATION ALERT : ONCOTARGET - CRCINA, INSERM - Nantes.

Sensitivity of pre-targeted immunoPET using 68Ga-peptide to detect colonic carcinoma liver metastases in a murine xenograft model: Comparison with 18FDG PET-CT


In this report the scientific team from CRCINA, INSERM Nantes demonstrated the improved performance of pretargeted immunoPET imaging with 68Ga-probes compared to gold standard 18FDG-PET in an orthotopic murine xenograft model of human colonic liver metastases. They used the PhotonIMAGERTM RT system to validate tumor implantation post intra-portal injection of luciferase transfected LS174T cells in nude mice and quantify Hepatic tumor burden prior to PET imaging.



Fanny Foubert, Sébastien Gouard, Catherine Saï-Maurel, Michel Chérel, Alain Faivre-Chauvet, David M. Goldenberg, Jacques Barbet, Clément Bailly, Caroline Bodet-Milin, Thomas Carlier, Françoise Kraeber-Bodéré, Yann Touchefeu and Eric Frampas.



DOI: 10.18632/oncotarget.25514

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