Biospace Lab News

June 25th, 2010

The National Institutes of Health in Bethesda, Maryland, USA has become the latest institute to take delivery of a Biospace Lab Photon Imager. Research Scientists at this famous American Research Center will soon be taking full advantage of the system's real time optical imaging technology, as well as the unique capabilities of the Photon Imager's 4View and MacroLens modules!

June 20th, 2010

The new 3D imaging module is now available for use with the Photon Imager! With the addition of this add-in module, the Photon Imager now has 4 dimensions - 3 spatial and one temporal, for the detection, localization and quantification of signal. 3D acquisitions are fast and signal analysis is helped greatly through use of M3 Vision 3D. Should you wish to upgrade your Photon Imager or are interested in the complete Photon Imager 3D system, please contact us straight away for more information

May 27th, 2010

A new Photon Imager system has just been installed in the Academic Medical Center in Amsterdam! Installation was celebrated in presence of the research team and the generous donor who made this purchase possible. A scientific presentation on the work of the team was given in the presence of the Dean of the University and the system’s use inaugurated by the donor, who performed the first image acquisition on the system using a bioluminescent source.
Biospace Lab is very proud to be part of this scientific venture and looks forward to actively supporting the research team from the AMC Amsterdam.

May 11th, 2010

Biospace Lab is glad to announce that the Photon Imager has now more than 40 publications, in fields as various as oncology, molecular imaging, neurosciences, infectious disease. The last publication describes studies made with special tracers based on the BRET mechanism that offers a red to NIR bioluminescent signal, for an improved sensitivity! In this example, the BRET molecules were used to image lymph nodes.
Download the application note from Zymera
Link to the article

April 1st, 2010

Biospace Lab moved to a new location in Paris on April 1st 2010. We are now located at 13, rue Georges Auric, in the 19th arrondissement and we look forward to hosting your visit to our new facilities in the near future!!
Directions to the 13 rue Georges Auric

January 2010

With the launch of the the Beta Imager D, the digital revolution continues! The Beta Imager-D features a new electronic design, and a new digital camera incorporating FireWire connectivity, which results in improved performance. Most notably, spatial resolution for the maximum field of view is improved to 175 microns, compared to 200 microns available previously.

December 2008

The Gamma Imager moves to the forefront of preclinical research on cartilage, thanks to the work of a research team headed by Nicole Moins, who characterized a SPECT radiotracer specific to articular joints. The modularity of the Gamma Imager made possible the use of planar and SPECT modes for both dynamic and static acquisitions. Such results may offer a unique opportunity to achieve a greater understanding of cartilage physiology in health and disease. Article available on line.

November 20th, 2008

Analytical Chemistry published an article on the experiments performed under a collaboration between the team of Professor Tavitian (CEA Orsay) and Biospace Lab using the In Actio add-in module for the Photon Imager in vivo optical imaging system. This short article is freely available on line.

October 3rd, 2008

New! A publication describing the technology behind the In Actio module for the Photon Imager system has been published in the Journal of Biomedical Optics. The article, which includes a description of the experimental validation performed using bioluminescent mice, is freely available on line.

June 20th-21st, 2008, Munich

Biospace Lab has participated in the creation of the European Network for Cell Imaging and Tracking Expertise (ENCITE), supported by the European Commission's 7th Framework Programme (FP7), and co-ordinated by the EIBIR (European Institute for Biomedical Imaging Research). Biospace Lab will be present at the Kick off meeting, held this week end in Munich.

June 18th, 2008, Paris

A major new paper which features the Biospace Lab Beta Microprobe has been published. A team headed by Philippe Lanièce (UMR8165 CNRS-University Paris 7 and Paris 11) describes in vivo kinetics measurement of 18F-MPPF binding in mouse hippocampus. Desbrée A, Verdurand M, Godart J, Dubois A, Mastrippolito R, Pain F, Pinot L, Delzescaux T, Gurden H, Zimmer L, Lanièce P: The Potential of a Radiosensitive Intracerebral Probe to Monitor ¹⁸F-MPPF Binding in Mouse Hippocampus In Vivo. J Nucl Med 2008 Jun 13 (2008).

List of all the betamicroprobe publications

June 2008, Paris

A potentially anti-cancerous molecule, named HB19, was characterized and studied for its effect on tumor growth and angiogenesis in vitro and in vivo. The Beta Imager was used to determine the biodistribution of the molecule after systemic administration in rats. Whole body autoradiography of the rats showed a fast clearance from the blood to tissues expressing significant levels of surface nucleotin, a cell surface protein involved in various processes like cell proliferation, differentiation and angiogenesis.

The article from PLoS ONE:
Destouches D, El Khoury D, Hamma-Kourbali Y, Krust B, Albanese P, Katsoris P, Guichard G, Briand JP, Courty J, Hovanessian A: Suppression of Tumor Growth and Angiogenesis by a Specific Antagonist of the Cell-Surface Expressed Nucleolin PLoS ONE, 3(6): e2518 (2008)

The article published in the French newspaper Le Monde (French):
Une équipe francaise découvre une molécule potentiellement anticancéreuse

List of all the Beta Imager publications

December, 2008

The Gamma Imager at the forefront of preclinical research on cartilage: the team of Nicole Moins characterized a SPECT radiotracer specific to articular joints. The modularity of the Gamma Imager made possible the use of planar and SPECT modes for both dynamic and static acquisitions. Such results may offer a unique opportunity to achieve a greater understanding of cartilage physiology in health and disease. Article avalaible on line.

June 20th-21st, 2008, Munich

Biospace Lab is participating to the creation of the European Network for Cell Imaging and Tracking Expertise (ENCITE), supported by the European Commission's 7th Framework Programme (FP7), and co-ordinated by the EIBIR (European Institute for Biomedical Imaging Research). Biospace Lab will be present at the Kick off meeting, held this week end in Munich.

June 18th, 2008, Paris

New! Major publication on Biospace Lab betamicroprobe. The team of Philippe Lanièce (UMR8165 CNRS-University Paris 7 and Paris 11) describes its work for in vivo kinetics measurements of the binding of ¹⁸F-MPPF in mouse hippocampus.

Desbrée A, Verdurand M, Godart J, Dubois A, Mastrippolito R, Pain F, Pinot L, Delzescaux T, Gurden H, Zimmer L, Lanièce P: The Potential of a Radiosensitive Intracerebral Probe to Monitor ¹⁸F-MPPF Binding in Mouse Hippocampus In Vivo. J Nucl Med 2008 Jun 13 (2008).

List of all the betamicroprobe publications

June 2008

A potentially anti-cancerous molecule, named HB19, was characterized and studied for its effect on tumor growth and angiogenesis in vitro and in vivo. The Beta Imager was used to determine the biodistribution of the molecule after systemic administration in rats. Whole body autoradiography of the rats showed a fast clearance from the blood to tissues expressing significant levels of surface nucleotin, a cell surface protein involved in various processes like cell proliferation, differentiation and angiogenesis.

The article from PLoS ONE:
Destouches D, El Khoury D, Hamma-Kourbali Y, Krust B, Albanese P, Katsoris P, Guichard G, Briand JP, Courty J, Hovanessian A: Suppression of Tumor Growth and Angiogenesis by a Specific Antagonist of the Cell-Surface Expressed Nucleolin PLoS ONE, 3(6): e2518 (2008)

The article published in the French newspaper Le Monde (French):
Une équipe francaise découvre une molécule potentiellement anticancéreuse

List of all the Beta Imager publications