Beta Microprobe
The probe is sensitive to Beta emitters including 11C, 18F, 32P, 131I, and provides a very low cost, simple alternative to µPET for pharmacokinetics, behavior studies, FDG studies, radiotracer development, and input function measurements among others.
Stereotaxically implanted in the animal brain, this unique microprobe allows users to measure
kinetics of a Beta labeled molecule on animals anesthetized or not, on short to long timescales,
in a well defined brain locus.
The probe can also be positioned in an organ, a tumor, or in a blood vessel
to measure the input function in a tracer experiment.
Fast, easy and quantitative biodistributions
On line kinetics measurements of 11C-raclopride binding after anaesthesia.
Two beta microprobes were implanted stereotaxically before the injection of the tracer.
Courtesy of V. Leviel and L. Zimmer, CERMEP, Lyon, France.
Courtesy of V. Leviel and L. Zimmer, CERMEP, Lyon, France.
Rat brain kinetics after three successive injections of 18F-FDG (0.5, 1 and 2 mCi).
Kinetics are recorded by two probes implanted in the striatum and cerebellum.
Courtesy of L. Besret and Ph. Hantraye, SHFJ Orsay, France.
Courtesy of L. Besret and Ph. Hantraye, SHFJ Orsay, France.
