Micro Imager
Image Atlas
10 minute acquisition of a 11C compound on a rat brain section
Courtesy of the PET center, Uppsala, Sweden
6 hour acquisition of rat brain sections using 5-HT1A PET ligand: 18F-MPPF
Courtesy of Prof. Luc Zimmer, CERMEP Lyon, France.
Infarcted myocardium from a rat, which was injected with 18FDG,
99mTc-Sestamibi and 111In-DTPPA prior to sacrifice.
Distributions from each of the 3 isotopes were discriminated from one single acquisition
and are shown with a different color each
Courtesy of S. Poussier.
S Poussier et al. J Nucl Cardiol: 12:229-30 2005
18FDG injected in a rat shows cortical activity after stimulus. Picture superimposed to a rat brain atlas.
Courtesy Prof. Tavitian, CEA SHFJ, Orsay, France.
Rat coronal brain section after injection of 700 µCi of 18FDG. After FDG injection and visual stimulation,
the rat was sacrificed and sections were imaged with different techniques: film, phosphor screens, Biospace Lab Beta Imager and Micro Imager.
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Courtesy Laurent Besret, Anne-Sophie Hérard and Fabrice Beau, URA CEA-CNRS 2210, Orsay, France
Autoradiographic image of rat tritium labeled kidney section
Courtesy Steve Harris, Roche, Welwyn, United Kingdom
Simultaneous imaging of the tracer 99mTc-NOET and the viability tracer 201Tl in a rat model of
chronic reperfused myocardial infarction.
Courtesy of Laurent Riou, INSERM, Grenoble and Carole Lartizien, CERMEP, Lyon.
Mouse femur sections showing a mantle-cell lymphoma tumor labeled with a 90Y-labeled anti-CD20.
Comparisons were made with histological sections to assess the antibody specificity.
Courtesy Jérémy Coulot, Marcel Ricard, Service de Physique, Institut Gustave Roussy, Villejuif,
France.
In situ hybridization of a 20 days mouse embryo using a 35S labeled probe specific to actin mRNA.
This was obtained after an overnight acquisition, whereas more than a week for a comparable acquisition with film.
The space between fingers is about 50 μm.
Courtesy of IPN, Orsay, France.
3H labeled mouse section (overnight acquisition).
Courtesy R. d'Argy, Active Biotech, Lund, Sweden.
This 14C labeled product specifically tags the choroid membrane of a rat eye.
Courtesy Dr Delbos, Laboratoires Servier, Orléans, France.
In-situ hybridization with two nucleic probes labeled with 3H and 14C.
Courtesy of the Riken Brain Research Institute, Japan.
The plant was labelled by short-duration pulse-chase feeding,
with radiolabelled metabolites, of the petiole of detached Arabidopsis
leaves. The leaves are then rapidly frozen and then freeze-dried, to
preserve the location of the label. Autoradiography reveals diverse
patterns of labelling within these leaves, depending on the location and
extent of cellular uptake of the compound fed. Simultaneous imaging of
two isotopes (3H and 14C) using the Micro Imager and Energy Dual-Labelling Software
allows comparison of the uptake pattern of two different metabolites
within a single sample. If a particular metabolite is fed as a control
in all samples, the variation in labelling pattern can be used to assess
the impact of inconsistent uptake of the feed solution due to wounding
or other factors.
The leaf was labelled with 3H GABA and 14C sucrose.
Separation of each isotope contribution to the image was performed with Biospace Lab Dual Energy Software.
The image opposite shows the biodistribution of 3H GABA, whereas the next image reveals that of the 14C sucrose in the same leaf.
Courtesy of Dr. Kinsman and Prof. Quick, Department of Animal and Plant
Sciences, University of Sheffield, UK.
Simultaneous imaging of two isotopes (3H and 14C) using the Micro Imager and Energy Dual-Labelling Software
allows comparison of the uptake pattern of two different metabolites
within a single sample.
The image opposite shows the biodistribution of 3H GABA, whereas the previous image reveals that of the 3H GABA in the same leaf.
Refer to the description of the previous image for detailed protocol.
Courtesy of Dr. Kinsman and Prof. Quick, Department of Animal and Plant
Sciences, University of Sheffield, UK.
Simultaneous imaging of two isotopes (3H and 14C) using the Micro Imager and Energy Dual-Labelling Software
Courtesy of Dr. Kinsman and Prof. Quick, Department of Animal and Plant
Sciences, University of Sheffield, UK.
Acquisition was performed four hours after the feeding of the seed s substending leaf with 14C carbon dioxide
Courtesy of Dr. Kinsman and Prof. Quick, Department of Animal and Plant
Sciences, University of Sheffield, UK.
