Beta Imager

Image Atlas

High throughput receptor occupancy studies The high sensitivity of the Beta imager is used to visualize and quantitatively analyze the [3H]senktide binding sites in brain sections within hours. Other traditional methods would take months to complete.
Courtesy of X. Langlois, Janssen Research Foundation, Beerse, Belgium.
[X. Langlois and al., JPET 299:712-717, 2001]

Ex vivo sessions after in vivo experiments
Rabbit brain: In vivo adminitered 99Tc labeled HMPAO complex (Hexe Methyl Propylen Amin Oxime)
Accumulation of the substance in the cortex, the thalamus, the hippocampus.
Courtesy of B. Basse-Cathalinat, Bordeaux, France.

Dual labelling
Rat tumor sections labeled with 3H (in red) and 14C (in green) labeled FDG
Courtesy of Vincent Dive, CEA, Gif sur Yvette, France.




Brain sections
3H labeled brain sections.
Courtesy of Pr. Porrino, Wake Forest University, United States.



Zoom option
Acquisition of 3H labeled brain sections with the zoom. Optical zoom for autoradiography acquisitions is obtained with the Beta Imager zoom option.
Courtesy of X. Langlois, Janssen Research Foundation, Beerse, Belgium.




Human brain sections
Tritium labeled sections of human brain. Acquisitions were obtained in 4 hours, vs 4 days for phosphor imagers, and 4 weeks for Fuji films.
Courtesy of Yasmin Hurd, Karolinska Institute, Stockholm, Sweden.






Tritium labeled whole body rat sections
Whole body rat section, labeled with tritium, and acquired for 15 hours. The upper image shows the acquisition performed on the full field of view, 200 x 250 mm2. The zoom was then used to get a more precise image of a field of view of 75 x 100 mm2 (lower image).
Courtesy of A. Molatt and P. Mitchell, Pfizer, United Kingdom.







Tritium labeled whole body rat section
Whole body rat section, labeled with tritium, and acquired for 15 hours with the zoom option for a field of view of 75 x 100 mm2.
Courtesy of A. Molatt and P. Mitchell, Pfizer, United Kingdom.